The Oxoadipic acid Diaries
123). It truly is noteworthy that GLS2 is tumorigenic in breast cancer124, and its expression could compensate for loss of Gls in MYC-induced mouse liver tumours40. This suggests that GLS2 could confer resistance to GLS1-particular inhibitors, including the allosteric inhibitor BPTES or CB-839, which resistance might be hypothetically prevented by